Actos (pioglitazone) is in the drug class thiazolidinediones and was approved by the U.S. Food and Drug Administration in 1999. Actos, manufactured by Takeda Pharmaceuticals, is prescribed along with dietary change and exercise in patients with Type 2 Diabetes to control their blood sugar. Actos decreases the amount of glucose (sugar) in the blood by making the cells more sensitive to insulin, while inhibiting the liver from producing more unnecessary glucose. In recent studies, research is suggesting a significant correlation between the use of Actos and cardiovascular complications and disease. The only other drug in the thiazolidinediones class is a similar drug called Avandia. In 2011, the FDA pulled Avandia from the U.S. market after being linked to an increased risk of heart attacks. In addition, Actos has already been removed from the market in Germany and France for concerns related to bladder cancer. The prescription drug now carries a warning label for the increased cancer risk, but remains on the market with the full support of the manufacturer. One of the reasons Actos has not yet been pulled from the U.S. market is because the drug companies insist they have nothing to replace it with. However, that does not justify the significant risk to patients who take the drug.
Studies are now showing that Actos does not present a marked decrease in cardiovascular risk versus Avandia and has nearly the same frequency by comparison.
It is not advisable to stop taking Actos without first speaking with your doctor. If you are currently taking Actos, proceed with extreme caution in regards to dosage and be aware of any warning signs of heart disease.
If you or a loved one has developed cardiovascular disease as a result of taking Actos, do not hesitate to contact our law firm today for a free consultation and case evaluation. You may be entitled to compensation for the harm Actos has caused.
The Migliore Law Firm located on Long Island, has represented clients in a wide range of product liability cases over the past three decades and has worked with nationally recognized co-counsel to reach successful verdicts. We work with other very successful law firms to provide you with the highest caliber legal help available and take every step necessary to obtain compensation on your behalf.
If you or someone you care about developed cardiovascular disease after taking Actos, contact the law firm of Rudolph F.X. Migliore, P.C. at (631) 543-3663 to arrange a free case evaluation.